Defeat any Apex Virus 10 times.

Help the robot find the lost bioshell.

Defeat a Great and Apex Virus, in the same run, without using your main attack.

Defeat The Source.

Learn enough about Deflector.

Defeat Horned Giant, the Apex Virus of Living Entrails, 3 times.

Defeat Bastions, the Great Virus of Living Entrails, 3 times.

Defeat Toxic Tentacles, the Apex Virus of Toxic Sea, 3 times.

Defeat Serpent, the Great Virus of Toxic Sea, 3 times.

Defeat Elite Sentinel, the Apex Virus of Magnetic Fields, 3 times.

Defeat Obelisk, the Great Virus of Magnetic Fields, 3 times.

Defeat Giant Centipedes, the Apex Virus of Hollow Hive, 3 times.

Defeat Giant Spider, the Great Virus of Hollow Hive, 3 times.

As Eradicator, complete all proficiency levels.

As Slasher, complete all proficiency levels.

As Gunslinger, complete all proficiency levels.

As Spark, complete all proficiency levels.

As Lightfist, complete all proficiency levels.

As Corrupted, complete all proficiency levels.

Pet Oogles 50 times.

Complete the game without using your active ability.

Complete the game with Virus Strain level 1.

Complete the game with Virus Strain level 2.

Complete the game with Virus Strain level 3.

Complete the game with Virus Strain level 4.

Complete the game with Virus Strain level 5.

Beat Living Entrails 10 times.

Beat Toxic Sea 10 times.

Beat Magnetic Fields 10 times.

Beat Hollow Hive 10 times.

Beat the game with Eradicator.

Beat the game with Slasher.

Beat the game with Gunslinger.

Beat the game with Spark.

Beat the game with Lightfist.

Beat the game with Corrupted.

Beat the game with all bioshells.

Complete a world without deflecting.

Survive for 30 minutes in the Survival Chamber.

Unlock all the neutral mutations.

Deflect 200 bombs in the Survival Chamber.

Buy an item with health.

Die for the first time.

Fill all your inventory with mutations.

Get the maximum buff of any altered state.

Fill all your inventory with mutations of the same family.

Reach the maximum upgrade level in any mutation.

Unlock all the upgrades.

Unlock all bioshells.

Buy 10 items in the shop in one run.

Reach level 7 of attack, deflect or support attribute.

Defeat a Great Virus without getting hit.

Defeat an Apex Virus without getting hit.

Parry 10 bullets with one deflect.

Apply 3 different altered states to a single enemy.

Use your active ability 50 times.

Complete a zone without visiting any safe point.

Complete a zone without spending cells.

Complete 30 mutation rooms.

Kill 30 enemies using word deflectables.

Defeat 100 enemies.

Defeat 1000 enemies.

Defeat 10000 enemies.

Complete your training.

Meet hunter for the first time.

As Eradicator, deflect your boomerang 500 times.

As Eradicator, kill 6 enemies with a single boomerang throw.

As Slasher, kill 150 enemies throwing your sword.

As Slasher, kill 6 enemies with a single use of the active ability.

As Gunslinger, kill 150 enemies with your turrets.

As Gunslinger, defeat 1 apex virus without dashing.

As Spark, defeat 150 enemies with recalled orbs.

As Spark, kill 10 enemies in a row with your orbit without taking any damage or stopping the orbit.

As Lightfist, throw 200 enemies into an obstacle.

As Lightfist, defeat the Great Virus of the second or third zone you visit without deflecting.

As Corrupted, defeat 150 enemies with attacks from the eye.

As Corrupted, complete 5 rooms in a row without losing your Immunity shield.